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Purine-nucleoside phosphorylase
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Purine-nucleoside phosphorylase : ウィキペディア英語版
Purine-nucleoside phosphorylase

In enzymology, a purine-nucleoside phosphorylase () is an enzyme that catalyzes the chemical reaction
:purine nucleoside + phosphate \rightleftharpoons purine + alpha-D-ribose 1-phosphate
Thus, the two substrates of this enzyme are purine nucleoside and phosphate, whereas its two products are purine and alpha-D-ribose 1-phosphate.
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is purine-nucleoside:phosphate ribosyltransferase. Other names in common use include inosine phosphorylase, PNPase, PUNPI, PUNPII, inosine-guanosine phosphorylase, nucleotide phosphatase, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside phosphorylase, and purine ribonucleoside phosphorylase. This enzyme participates in 3 metabolic pathways: purine metabolism, pyrimidine metabolism, and nicotinate and nicotinamide metabolism.
==Structural studies==

As of late 2007, 85 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , and .

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